AMD MI50 32GB vs AMD Instinct MI210 for local LLMs
12 reports on the AMD MI50 32GB and 0 on the AMD Instinct MI210
Which is faster for local LLMs?
Nobody has reported the same model at the same quant on both cards yet, so there's no measured head-to-head. Memory bandwidth, which caps how fast a card can write, is 1.6x higher on the AMD Instinct MI210 (1,024 GB/s on the AMD MI50 32GB, 1,638 on the AMD Instinct MI210). The estimates below compare them on the models people run most.
AMD MI50 32GB
- Memory
- 32GB
- Memory bandwidth
- 1,024 GB/s
- FP16 compute
- 26.5 TFLOPS
- Reports
- 12
AMD Instinct MI210
- Memory
- 64GB
- Memory bandwidth
- 1,638 GB/s
- FP16 compute
- 181 TFLOPS
- Reports
- 0
Estimated by the calculator
The quant the calculator recommends for each card and its estimated speed at a 32,768-token context with 32 GB of system RAM, from memory bandwidth and the model's shape.
| Model | AMD MI50 32GB | AMD Instinct MI210 |
|---|---|---|
| Qwen3.8 27B | 25.7 t/sQ6_K | 33.4 t/sQ8_0 |
| Qwen3.8 125B · 6B active | 19.6 t/sQ2_K, experts in RAM | 139.4 t/sQ3_K_S |
| DeepSeek V4 Flash 284B · 13B active | doesn't fit at these settings | doesn't fit at these settings |
| Qwen3.6 35B · 3B active | 93.1 t/sQ5_K_M | 120.1 t/sQ8_0 |
| Qwen3.6 27B | 25.7 t/sQ6_K | 33.4 t/sQ8_0 |
| Gemma 4 26B · 4B active | 65.4 t/sQ6_K | 90.1 t/sQ8_0 |
Change the context, RAM or model in the calculator: AMD MI50 32GB · AMD Instinct MI210
Every report on each card, with its source: AMD MI50 32GB · AMD Instinct MI210